NONPARAMETRIC REGRESSION WITH MEASUREMENT ERROR: SOME RECENT PROGRESS David Ruppert In nonparametric regression we estimate the conditional expectation of a response Y given a covariate X without assuming a parametric structure for this function. In regression with measurement error, we do not observe X itself but rather a proxy W which is commonly assumed to be X plus measurement error. Nonparametric regression without measurement error has been studied extensively. Moreover, parametric regression with measurement error is now a well developed field with monographs by Fuller (1987) and Carroll, Ruppert, and Stefanski (1995). It is perhaps surprising then, that there has been little work on nonparametric regression with measurement error. This lack of research may indicate the difficulty of the problem. Before the work of Carroll and Ruppert and their coworkers, Jeff Maca and Scott Berry, only the paper by Fan and Truong (1993, Annals) was available. We now have several efficient methodologies for nonparametric regression with mismeasured X's: SIMEX and local polynomial regression, SIMEX with penalized splines, a flexible structural spline method, and a fully Bayesian spline method. These methodologies will be explained and compared. The slides and references for this talk are available at: www.orie.cornell.edu/~davidr (link to "recent lectures")